Published on may 22, in <em>The Lancet</em>, the study concluded that hydroxychloroquine is not beneficial to the sick of the COVID-19 hospitalized, and can even be detrimental.
June 4, 2020 16h43
Hydroxychloroquine: three authors of the study in the Lancet retract
PARIS — Three of the four authors of the controversial paper published in the Lancet on the use of hydroxychloroquine against the COVID-19 have requested the retraction of the article, announced that the journal The Lancet on Thursday evening.
“We can’t vouch for the veracity of the sources of primary data,” write the three authors of the Lancet, involving the refusal of the company which collected it, led by the fourth author, to give access to the database.
Published may 22 in The Lancet, the study concluded that hydroxychloroquine is not beneficial to the sick of the COVID-19 hospitalized, and can even be detrimental.
Its release had been a worldwide coverage and dramatic effect, pushing in particular the WHO (world health Organization) to suspend clinical trials of hydroxychloroquine against the COVID-19.
But finally, after many critics questioning the methodology of the study, including the share of scientists who are skeptical of the benefit of hydroxychloroquine in the treatment of the COVID-19, the WHO announced on Wednesday the resumption of clinical trials with this molecule.
The critics were especially concerned that the data on which were based the study (96 000 patients hospitalized between December and April in 671 hospitals, harvested) harvested by the american society Surgisphere, led by the fourth author Sapan Desai.
“We have launched an independent analysis of Surgisphere with the agreement of Sapan Desai to assess the origin of the elements of the database, confirm that it was complete and replicate the analyses presented in the article “, write the other three authors in the text published by the Lancet.
But Surgisphere refused to transfer the database because of confidentiality agreements with its customers (hospitals in the origin of the data), the experts wanderers ” have not been able to conduct an independent review and have informed us of their withdrawal from the process of peer review “, they add.